The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2019
Filed:
Aug. 10, 2015
Applicants:
Michael J Powell, Alamo, CA (US);
Aiguo Zhang, San Ramon, CA (US);
Inventors:
Michael J Powell, Alamo, CA (US);
Aiguo Zhang, San Ramon, CA (US);
Assignee:
DIACARTA LTD, George Town, KY;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/6858 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6858 (2013.01); C12Q 1/6858 (2013.01); C12Q 2525/113 (2013.01); C12Q 2537/143 (2013.01); C12Q 2537/163 (2013.01);
Abstract
The invention relates to a method for enriching a target polynucleotide sequence containing a genetic variation said method comprising: (a) providing two primers targeted to said target polynucleotide sequence; (b) providing a target specific xenonucleic acid clamp oligomer specific for a wildtype polynucleotide sequence; (c) generating multiple amplicons using PCR under specific temperature cycling conditions; and (d) detecting said amplicons.