The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2019
Filed:
Jan. 29, 2016
Applicant:
Larry J. Smith, Omaha, NE (US);
Inventor:
Larry J. Smith, Omaha, NE (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/712 (2006.01); A61K 31/7125 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 31/712 (2013.01); A61K 31/713 (2013.01); A61K 31/7125 (2013.01); C12N 15/113 (2013.01); C12N 15/1136 (2013.01); C12N 15/1137 (2013.01); C12N 15/1138 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/31 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/3513 (2013.01); C12N 2310/51 (2013.01); C12N 2320/31 (2013.01); C12N 2320/35 (2013.01); C12N 2320/51 (2013.01);
Abstract
Compositions and method for down modulating target gene expression which RNA interference, as well as methods for administering said compositions are disclosed. The method comprises administering a first oligonucleotide strand to a cell, incubating the cells for a time period suitable for uptake of the first oligo nucleotide strand prior to administration of a second oligonucleotide strand, wherein the first strand and the second strand form an intracellular duplex which is effective to catalyze degradation of gene target mRNA or inhibit translation of said mRNA.