IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10385022 B1

PDFFull Text
Date of Patent:
Aug. 20, 2019

Filed:

Feb. 06, 2015

3-amino-pyridines as gpbar1 agonists

Applicant:

Hoffmann-la Roche Inc., Nutley, NJ (US);

Inventors:

Caterina Bissantz, Village-Neuf, FR;

Henrietta Dehmlow, Loerrach, DE;

Shawn David Erickson, Leonia, NJ (US);

Prabha Saba Karnachi, Hillsborough, NJ (US);

Kyungjin Kim, Livingston, NJ (US);

Rainer E. Martin, Basel, CH;

Patrizio Mattei, Riehen, CH;

Ulrike Obst Sander, Reinach BL, CH;

Sherrie Lynn Pietranico-Cole, Montclair, NJ (US);

Hans Richter, Grenzach-Wyhlen, DE;

Christoph Ullmer, Fischingen, DE;

Assignee:

HOFFMANN-LA ROCHE INC., Nutley, NJ (US);

Attorney:
Primary Examiner:

Leslie A Royds Draper

Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 213/82 (2006.01); C07D 213/75 (2006.01); C07D 213/81 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 417/04 (2006.01); C07D 417/12 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 213/75 (2013.01); C07D 213/81 (2013.01); C07D 213/82 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 413/04 (2013.01); C07D 413/12 (2013.01); C07D 417/04 (2013.01); C07D 417/12 (2013.01); C07D 491/107 (2013.01);
Abstract

This invention relates to novel 3-aminopyridines of the formula wherein B, Band Rto Rare as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.

Find Patent Forward Citations

Loading…