The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2019

Filed:

Sep. 05, 2014
Applicant:

Glycom A/s, Hørsholm, DK;

Inventors:

Gyula Dekany, Sinnamon Park, AU;

Pauline Peltier-Pain, Orleans, FR;

Dóra Molnár-Gábor, Budapest, HU;

Markus Jondelius Hederos, Trelleborg, SE;

Assignee:

Glycom A/S, Hørsholm, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/18 (2006.01); C07H 3/06 (2006.01); C12P 19/26 (2006.01); C08B 37/00 (2006.01); C12P 19/00 (2006.01);
U.S. Cl.
CPC ...
C12P 19/18 (2013.01); C07H 3/06 (2013.01); C08B 37/006 (2013.01); C12P 19/00 (2013.01); C12P 19/26 (2013.01); C12Y 204/01065 (2013.01); C12Y 204/01087 (2013.01); C12Y 204/01099 (2013.01);
Abstract

The application discloses a method for producing an oligosaccharide of at least four monosaccharide units, advantageously an HMO, particularly an HMO of only four monosaccharide units, said method comprising a step of: culturing, in a culture medium containing a fucosylated, sialylated or N-acetyl-glucosaminylated lactose trisaccharide as acceptor, a genetically modified cell having a recombinant gene that encodes an enzyme capable of modifying said acceptor or one of the necessary intermediates in the biosynthetic pathway of the oligosaccharide of at least four monosaccharide units, advantageously an HMO, particularly an HMO of only four monosaccharide units, from said acceptor.


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