The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Aug. 25, 2017
Applicants:
The Charlotte-mecklenburg Hospital Authority, Charlotte, NC (US);
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Inventors:
Qi Long Lu, Charlotte, NC (US);
Xiao Xiao, Chapel Hill, NC (US);
Assignees:
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, Chapel Hill, NC (US);
THE CHARLOTTE MECKLENBURG HOSPITAL AUTHORITY, Charlotte, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07K 14/47 (2006.01); A61K 38/17 (2006.01); C12N 15/86 (2006.01); C12N 9/10 (2006.01); A01K 67/027 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A01K 67/0275 (2013.01); A61K 38/1719 (2013.01); C07K 14/4707 (2013.01); C12N 9/10 (2013.01); C12N 15/86 (2013.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A61K 38/00 (2013.01); C12N 2750/14143 (2013.01); C12N 2800/22 (2013.01); C12N 2830/008 (2013.01);
Abstract
The invention relates to synthetic polynucleotides encoding fukutin related protein (FKRP). The invention further relates to nucleic acid constructs comprising the synthetic polynucleotides and methods of using these synthetic polynucleotides to treat dystroglycanopathy disorders.