The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Nov. 26, 2014
Applicant:
The University of Chicago, Chicago, IL (US);
Inventors:
Jared C. Lewis, Chicago, IL (US);
Catherine Poor, Chicago, IL (US);
Mary Andorfer, Chicago, IL (US);
James Payne, Chicago, IL (US);
Assignee:
The University of Chicago, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12P 13/22 (2006.01); C12P 17/10 (2006.01); C12P 17/18 (2006.01); C12P 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0071 (2013.01); C12P 5/005 (2013.01); C12P 13/227 (2013.01); C12P 17/10 (2013.01); C12P 17/182 (2013.01); C12Y 114/14007 (2013.01); C12Y 114/14009 (2013.01);
Abstract
Compounds and methods are providing involving RebH variants with improved properties. directed evolution based on random mutagenesis was employed to generate a series of RebH variants. RebH variants with improved thermostability and increased activity at elevated temperatures were generated.