The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2019
Filed:
Mar. 13, 2014
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Loren D. Walensky, Newton, MA (US);
Gregory H. Bird, Pelham, NH (US);
Woojin Kim, Newton, MA (US);
Stuart Orkin, Brookline, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/96 (2006.01); A61K 38/00 (2006.01); A61K 35/00 (2006.01); A61K 38/12 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 14/47 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 9/96 (2013.01); C07K 14/47 (2013.01); C12N 9/1007 (2013.01); A61K 38/00 (2013.01); C12Y 201/01043 (2013.01);
Abstract
Provided herein are polypeptides containing stabilized therapeutic peptides related to enhancer of zeste homolog 2 (EZH2), histone lysine N-methyltransferase. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.