The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2019

Filed:

Sep. 06, 2016
Applicant:

Basf Plant Science Gmbh, Ludwigshafen, DE;

Inventors:

Petra Cirpus, Mannheim, DE;

Jörg Bauer, Limburgerhof, DE;

Xiao Qiu, Saskatoon, CA;

Guohai Wu, Saskatoon, CA;

Bifang Cheng, Saskatoon, CA;

Martin Truksa, Saskatoon, CA;

Tom Wetjen, Mannheim, DE;

Assignee:

BASF Plant Science GmbH, Ludwigshafen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/20 (2006.01); C12N 15/82 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 15/52 (2006.01); C12P 7/64 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8247 (2013.01); C12N 9/0071 (2013.01); C12N 9/0083 (2013.01); C12N 9/1029 (2013.01); C12N 15/52 (2013.01); C12P 7/6427 (2013.01); C12Y 114/19 (2013.01);
Abstract

The invention relates to a method for producing eicosapentaenoic acid, docosapentaenoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.


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