The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Feb. 24, 2015
Applicant:

Erber Aktiengesellschaft, Getzersdorf bei Traismauer, AT;

Inventors:

Markus Aleschko, Vienna, AT;

Corinna Kern, Vienna, AT;

Dieter Moll, Stockerau, AT;

Eva Maria Binder, Tulln, AT;

Gerd Schatzmayr, Tulln, AT;

Assignee:

ERBER AKTIENGESELLSCHAFT, Getzersdorf bei Traismauer, AT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/18 (2006.01); C12N 15/55 (2006.01); A23K 10/14 (2016.01); A23K 50/30 (2016.01); A23K 50/60 (2016.01); A23K 20/147 (2016.01); C12N 1/21 (2006.01);
U.S. Cl.
CPC ...
A23K 10/14 (2016.05); A23K 20/147 (2016.05); A23K 50/30 (2016.05); A23K 50/60 (2016.05); C12N 9/18 (2013.01);
Abstract

The invention relates totoxin-cleaving polypeptide variants of atoxin carboxyl esterase with the SEQ ID NO:46. Each of the polypeptide variants has an amino acid sequence shortened by 47 amino acids at the N terminus, and the amino acid sequences have at least 70%, preferably 80%, in particular 100%, sequence identity, namely SEQ ID NO:1, to the amino acid sequence portion 48-540 of the SEQ ID NO:46. The invention also relates to isolated polynucleotides which code for the polypeptide variants, to atoxin-cleaving additive containing at least one polypeptide variant and optionally at least one auxiliary agent, to the use of the polypeptide variants or the additive, and to a method for hydrolytically cleaving at least onetoxin.


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