The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2019
Filed:
Mar. 03, 2017
Applicant:
Arqule, Inc., Burlington, MA (US);
Inventors:
Jean-Marc Lapierre, Pelham, NH (US);
Sudharshan Eathiraj, Shrewsbury, MA (US);
Nivedita Namdev, Westford, MA (US);
Brian Schwartz, Woodbridge, CT (US);
Yusuke Ota, Tokyo, JP;
Takayuki Momose, Tokyo, JP;
Tomoyuki Tsunemi, Tokyo, JP;
Hiroaki Inagaki, Tokyo, JP;
Kiyoshi Nakayama, Tokyo, JP;
Assignee:
ArQule, Inc., Burlington, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); C07D 487/04 (2013.01);
Abstract
The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.