The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 02, 2019

Filed:

Mar. 01, 2013
Applicant:

The University Court of the University of Edinburgh, Edinburgh, GB;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A01K 67/027 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0276 (2013.01); A01K 67/0275 (2013.01); C07K 14/4702 (2013.01); C12N 9/22 (2013.01); A01K 2217/07 (2013.01); A01K 2217/072 (2013.01); A01K 2217/075 (2013.01); A01K 2227/108 (2013.01); A01K 2267/02 (2013.01); A01K 2267/03 (2013.01);
Abstract

The present invention relates to a genetically edited animal, especially to a genetically edited pig in which expression or activity of the RELA protein has been modified. Such pigs have at least partial protection against the African Swine Fever Virus. The invention also provides, a cell nucleus, germ cell, stem cell, gamete, blastocyst, embryo, foetus and/or donor cell of a non-human animal comprising a genetic modification which alters the expression or function of RELA protein, methods for editing the genome of animals and methods for screening the efficacy of a pharmaceutical agent in such an animal.


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