The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Nov. 06, 2014
Bristol-myers Squibb Company, Princeton, NJ (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Irene M. Ghobrial, Wellesley, MA (US);
Aldo M. Roccaro, Boston, MA (US);
Josephine M. Cardarelli, San Carlos, CA (US);
Antonio Sacco, Boston, MA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present disclosure provides a method for treating a subject afflicted with Waldenstrm's macroglobulinemia (WM) comprising administering to the subject a therapeutically effective amount of an antibody or an antigen-binding portion thereof that specifically binds to a CXCR4 receptor expressed on the surface of a WM cell. The disclosure also provides a therapeutic regimen for treating a patient afflicted with C1013G/CXCR4-associated WM.