The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Aug. 30, 2016
Applicant:

Board of Trustees of Michigan State University, East Lansing, MI (US);

Inventors:

Merlin L. Bruening, East Lansing, MI (US);

Gregory L. Baker, East Lansing, MI (US);

Somnath Bhattacharjee, Durham, NC (US);

Yiding Ma, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01D 67/00 (2006.01); G01N 1/34 (2006.01); B01J 20/28 (2006.01); B01D 15/38 (2006.01); B01J 47/12 (2017.01); B01J 20/32 (2006.01); B01J 20/22 (2006.01); C07K 1/22 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
B01D 67/0088 (2013.01); B01D 15/3828 (2013.01); B01J 20/22 (2013.01); B01J 20/28033 (2013.01); B01J 20/327 (2013.01); B01J 20/328 (2013.01); B01J 20/3265 (2013.01); B01J 47/12 (2013.01); C07K 1/22 (2013.01); G01N 1/34 (2013.01); G01N 33/54306 (2013.01); Y10T 428/249991 (2015.04); Y10T 436/25375 (2015.01);
Abstract

The disclosure relates to a process and related article for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization.


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