The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

May. 04, 2015
Applicant:

Signalrx Pharmaceuticals, Inc., San Diego, CA (US);

Inventors:

Guillermo A Morales, Oro Valley, AZ (US);

Joseph R. Garlich, Volcano, HI (US);

Kevin T. Weber, Carmel, IN (US);

Jessica M. Newblom, Indianapolis, IN (US);

Donald L. Durden, San Diego, CA (US);

Assignee:

SignalRx Pharmaceuticals, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 495/04 (2006.01); C07D 487/04 (2006.01); C07D 473/18 (2006.01);
U.S. Cl.
CPC ...
C07D 473/18 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01);
Abstract

The invention relates to compounds of Formulas I-VII (or pharmaceutically acceptable salts thereof) as defined herein, pharmaceutical compositions thereof, and their use in manufactures and methods for modulating cellular signaling pathways and biological processes associated therewith including inhibition of kinase activity such as PI-3 kinase or inhibition of bromodomain proteins or both at the same time as well as to therapeutic methods for treating a disease associated with aberrant PI3K and/or bromodomain proteins.


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