The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
May. 27, 2016
Applicant:
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Thomas Harding, San Francisco, CA (US);
Kristen Pierce, Burlingame, CA (US);
Namrata Patil, Sunnyvale, CA (US);
Thomas Brennan, San Jose, CA (US);
Julie Hambleton, San Francisco, CA (US);
Assignee:
Five Prime Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/24 (2006.01); A61K 31/337 (2006.01); A61K 31/513 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/337 (2013.01); A61K 31/513 (2013.01); A61K 33/24 (2013.01); A61K 45/06 (2013.01); C07K 16/2863 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01); C07K 2317/41 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.