The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2019
Filed:
Aug. 18, 2017
Signal Pharmaceuticals, Llc, San Diego, CA (US);
Jan Elsner, Solana Beach, CA (US);
Roy L. Harris, San Diego, CA (US);
Branden Gingsee Lee, San Diego, CA (US);
Deborah Mortensen, San Diego, CA (US);
Garrick K. Packard, Humbird, WI (US);
Patrick Papa, Carlsbad, CA (US);
Jason Parnes, San Diego, CA (US);
Sophie Perrin-Ninkovic, La Jolla, CA (US);
Jennifer Riggs, Cardiff, CA (US);
John Sapienza, Chula Vista, CA (US);
Graziella I. Shevlin, Lima, PE;
Lida Tehrani, San Diego, CA (US);
Jingjing Zhao, San Diego, CA (US);
Signal Pharmaceuticals, LLC, San Diego, CA (US);
Abstract
Provided herein are methods for the preparation of substituted pyrazino[2,3-b]pyrazines of the formula (II): the method comprising contacting a compound of formula (VI): with R—Y in a solvent, in the presence of a palladium catalyst, wherein said contacting occurs in the presence of a base, wherein R-R, Y, the palladium catalyst and the base are as defined herein.