The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
May. 31, 2013
Duke University, Durham, NC (US);
Janssen Diagnostics, Llc, Raritan, NJ (US);
Galla Chandra Rao, Princeton Junction, NJ (US);
Mark C. Connelly, Doylestown, PA (US);
Mariano A. Garcia-Blanco, Hillsborough, NC (US);
Andrew J. Armstrong, Chapel Hill, NC (US);
Rhonda L. Bitting, Durham, NC (US);
Duke University, Durham, NC (US);
Janssen Diagnostics, LLC, Raritan, NJ (US);
Abstract
Provided are methods for detecting or isolating circulating tumor cells (CTCs) in a subject. The methods may include detecting the expression of at least one epithelial mesenchymal transition (EMT) biomarker. Further provided are kits for detecting or isolating CTCs. The kits may include antibodies to at least one EMT biomarker. Further provided are methods of predicting the responsiveness of a subject to a cancer drug, methods of targeting delivery of a cancer drug in a subject, methods of providing a cancer prognosis to a subject, and methods for following the progress of cancer in a subject.