The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Feb. 24, 2017
Applicant:
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Inventors:
William F. Goins, Pittsburgh, PA (US);
Joseph C. Glorioso, III, Pittsburgh, PA (US);
Justus Bernard Cohen, Pittsburgh, PA (US);
Bonnie L. Reinhart, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/16 (2006.01); A61K 38/46 (2006.01); A61K 48/00 (2006.01); C07K 14/47 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
C12N 9/16 (2013.01); A61K 38/46 (2013.01); A61K 48/005 (2013.01); C07K 14/4703 (2013.01); A61K 9/0019 (2013.01); A61K 9/0085 (2013.01); A61K 9/08 (2013.01); A61K 47/02 (2013.01); C12N 2710/16643 (2013.01); C12N 2799/028 (2013.01); C12N 2830/008 (2013.01);
Abstract
The invention provides a method for ameliorating chronic pain signaling involving transient receptor potential cation channel subfamily V member 1 (TRPV1) by expressing PP1α in neurons. The invention also provides HSV vectors for expressing PP1α within neurons and compositions comprising such vectors.