The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Sep. 28, 2017
Dong-a St Co., Ltd., Seoul, KR;
Sun-Ho Choi, Seoul, KR;
Weon-Bin Im, Gyeonggi-do, KR;
Sung-Hak Choi, Gyeonggi-do, KR;
Chong-Hwan Cho, Gyeonggi-do, KR;
Ho-Sang Moon, Gyeonggi-do, KR;
Jung-Sang Park, Gyeonggi-do, KR;
Min-Jung Lee, Gyeonggi-do, KR;
Hyun-Jung Sung, Gyeonggi-do, KR;
Jun-Hwan Moon, Gyeonggi-do, KR;
Seung-Hyun Song, Gyeonggi-do, KR;
Hyung-Keun Lee, Seoul, KR;
Ji-Hoon Choi, Gyeonggi-do, KR;
Cheon-Hyoung Park, Seoul, KR;
Yoon-Jung Kim, Gyeonggi-do, KR;
Jin-Hyuk Kim, Gyeonggi-do, KR;
Dong-A St Co., Ltd., Seoul, KR;
Abstract
The present disclosure relates to a novel tetrahydropyridine derivative compound, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, methods for preparing the compounds, methods for inhibiting UDP-3-O—(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), methods for treating Gram-negative bacterial infections, the use of the compounds for the preparation of therapeutic medicaments for treating Gram-negative bacterial infections, and pharmaceutical compositions for prevention or treatment of Gram-negative bacterial infections, which contain the compounds. The compounds represented by formula I, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present disclosure can exhibit excellent effects on the treatment bacterial infections.