The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Sep. 22, 2009
Applicants:

Anastasia Khvorova, Westborough, MA (US);

William Salomon, Worcester, MA (US);

Joanne Kamens, Newton, MA (US);

Dmitry Samarsky, Westborough, MA (US);

Tod M. Woolf, Sudbury, MA (US);

Michelle Miller, Norwood, MA (US);

Karen G. Bulock, Mendon, MA (US);

Inventors:

Anastasia Khvorova, Westborough, MA (US);

William Salomon, Worcester, MA (US);

Joanne Kamens, Newton, MA (US);

Dmitry Samarsky, Westborough, MA (US);

Tod M. Woolf, Sudbury, MA (US);

Michelle Miller, Norwood, MA (US);

Karen G. Bulock, Mendon, MA (US);

Assignee:

RXi Pharmaceuticals Corporation, Marlborough, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/3515 (2013.01); C12N 2310/3519 (2013.01); C12N 2310/3521 (2013.01); C12N 2320/32 (2013.01); C12N 2320/51 (2013.01); C12N 2320/53 (2013.01);
Abstract

Neutral lipid formulations for nucleic acid delivery are provided according to the invention. The neutral lipid formulations include hydrophobically modified polynucleotides and fat mixtures. Methods of using the neutral lipid formulations are also provided.


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