The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Jan. 22, 2018
Applicants:
Zhiming Rao, Wuxi, CN;
Meizhou Wang, Wuxi, CN;
Meijuan Xu, Wuxi, CN;
Xian Zhang, Wuxi, CN;
Taowei Yang, Wuxi, CN;
Inventors:
Zhiming Rao, Wuxi, CN;
Meizhou Wang, Wuxi, CN;
Meijuan Xu, Wuxi, CN;
Xian Zhang, Wuxi, CN;
Taowei Yang, Wuxi, CN;
Assignee:
Jiangnan University, Wuxi, JS, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/10 (2006.01); C12N 15/77 (2006.01); C12N 9/78 (2006.01); C12R 1/15 (2006.01);
U.S. Cl.
CPC ...
C12P 13/10 (2013.01); C12N 9/78 (2013.01); C12N 15/77 (2013.01); C12Y 305/03006 (2013.01); C12R 1/15 (2013.01);
Abstract
Disclosed is a method for producing L-citrulline using recombinantcells as whole-cell biocatalysts. The present invention provides a recombinantthat expresses an exogenous arginine deiminase gene from. The recombinantSDNN403 is used as biocatalysts for converting L-arginine to produce L-citrulline. Using the method of the invention, the concentration of L-citrulline reached 301.4 g/L after a 48 hr conversion reaction, and the molar conversion rate reached 99.9%.