The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Sep. 10, 2012
Applicants:
Li-huei Tsai, Cambridge, MA (US);
Yingwei Mao, Arlington, MA (US);
Jon Madison, Newton, MA (US);
Stephen J. Haggarty, Gloucester, MA (US);
Inventors:
Li-Huei Tsai, Cambridge, MA (US);
Yingwei Mao, Arlington, MA (US);
Jon Madison, Newton, MA (US);
Stephen J. Haggarty, Gloucester, MA (US);
Assignees:
Massachusetts Institute of Technology, Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/00 (2006.01); A61K 38/17 (2006.01); A61K 31/00 (2006.01); A61K 31/351 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 31/00 (2013.01); A61K 31/351 (2013.01); A61K 31/40 (2013.01);
Abstract
The invention relates to methods of treating neurological disorders in a subject, by activating a DISC1 pathway. Methods of promoting neurogenesis in adult neural progenitor cells, enhancing nerve generation and treating GSK3 disorders as well as related compositions are also provided.