The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2018
Filed:
Aug. 01, 2017
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Assignee:
ACADEMIA SINICA, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/02 (2006.01); G01N 33/58 (2006.01); C07F 5/02 (2006.01); C07K 7/08 (2006.01); G01N 21/64 (2006.01); C07D 309/14 (2006.01);
U.S. Cl.
CPC ...
G01N 33/582 (2013.01); C07D 309/14 (2013.01); C07D 311/02 (2013.01); C07F 5/027 (2013.01); C07K 7/08 (2013.01); G01N 21/64 (2013.01); G01N 2333/924 (2013.01); G01N 2458/30 (2013.01);
Abstract
Provided are azido-BODIPY compounds of formula (I), cyclooctyne-based fluorogenic probes of formula (IV), and activity-based probes of formula (VI). These compounds undergo azide-alkyne cycloadditions (AAC) with to form triazolyl products. The provided compounds are useful for detection and imaging of alkyne-, or azide-containing molecules. Methods for detection and imaging biomolecules using compounds of the present disclosure are disclosed.