The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2018
Filed:
Sep. 14, 2017
Harpoon Therapeutics, Inc., South San Francisco, CA (US);
Robert B. Dubridge, Belmont, CA (US);
Pui Seto, San Carlos, CA (US);
Richard J. Austin, San Francisco, CA (US);
Luke Evnin, San Francisco, CA (US);
Jeanmarie Guenot, San Francisco, CA (US);
Bryan D. Lemon, Mountain View, CA (US);
HARPOON THERAPEUTICS, INC., South San Francisco, CA (US);
Abstract
Disclosed herein are single chain variable fragment CD3 binding proteins with improved binding affinities, and robust aggregation profiles. Also described are multispecific binding proteins comprising a single chain variable fragment CD3 binding protein according to the instant disclosure. Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of using such formulations are provided.