The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2018

Filed:

Aug. 27, 2015
Applicant:

Codexis, Inc., Redwood City, CA (US);

Inventors:

Gjalt W. Huisman, Redwood City, CA (US);

Jed Lee Hubbs, Thalwil, CH;

Xiyun Zhang, Fremont, CA (US);

Robert Osborne, Raleigh, NC (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 401/14 (2006.01); C07D 239/22 (2006.01); C07D 233/54 (2006.01); C07C 59/185 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); C07C 59/185 (2013.01); C07D 233/54 (2013.01); C07D 239/22 (2013.01); C07D 401/14 (2013.01);
Abstract

The present invention provides kinase inhibitor analogs with improved properties, such as improved efficacy, pharmacokinetics, safety, and specificity. In some embodiments, the present invention provides nilotinib analogs that provide therapeutic benefits.


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