The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2018

Filed:

Sep. 09, 2016
Applicant:

Indiana University Research and Technology Corporation, Indianapolis, IN (US);

Inventors:

Mark Goebl, Indianapolis, IN (US);

Cary Woods, Indianapolis, IN (US);

Ross Cocklin, Indianapolis, IN (US);

Josh Heyen, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12P 1/02 (2006.01); C12P 7/00 (2006.01); C12Q 1/68 (2018.01); C07H 21/04 (2006.01); C12N 1/18 (2006.01); C12N 15/01 (2006.01); C12P 7/06 (2006.01);
U.S. Cl.
CPC ...
C12N 1/18 (2013.01); C12N 15/01 (2013.01); C12P 7/00 (2013.01); C12P 7/06 (2013.01); Y02E 50/16 (2013.01);
Abstract

Disclosed herein are materials and methods for creating and/or isolating variants of yeasts especially variants ofthat can grow on sugars other than D-glucose in the presence of amounts of 2-deoxy-glucose and or D-glucose that inhibit most strains of yeast from growing on sugars other than D-glucose. Selection media that can be used to isolate such variants include pentose sugars such as D-xylose, L-glutamine and 2-deoxy-glucose. Mutations in the Grr1 and Red genes in some strains also produce variants that can grow on sugars including the pentose D-xylose in the presence of 2-deoxy-glucose.


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