The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 03, 2018

Filed:

Sep. 17, 2015
Applicant:

Zhejiang Medicine Co., Ltd., Xinchang Pharmaceutical Factory, Xinchang, Zhejiang, CN;

Inventors:

Yongjian Peng, Zhejiang, CN;

Xinde Xu, Zhejiang, CN;

Bin Shao, Zhejiang, CN;

Lihua Zhang, Zhejiang, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 51/09 (2006.01); C11C 3/10 (2006.01); C11B 7/00 (2006.01); C07C 67/02 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
C07C 51/09 (2013.01); C07C 67/02 (2013.01); C11B 7/0058 (2013.01); C11C 3/10 (2013.01); C11B 7/0041 (2013.01); G01N 30/02 (2013.01); G01N 2030/027 (2013.01);
Abstract

A method for preparing high-content conjugated linoleic acid (CLA) through purification of vegetable oil includes alcoholysis, purification and isomerization of vegetable oil. Alcoholysis is for preparing corresponding methyl ester or ethyl ester with glyceride; purification of methyl ester or ethyl ester is for obtaining methyl linoleate or ethyl linoleate of content over 85% through silver-based silica gel column chromatography; high-content CLA is obtained after alkali-catalyzed conjugation of methyl linoleate or ethyl linoleate, and CLA products are prepared as needed. This invention changes the status quo of preparing high-content CLA with safflower oil alone, expands sources of CLA, and develops an efficient technology for separation and purification of linoleic acid. The CLA obtained is of high purity and meets applications in pharmaceutical, health care products and other industries.


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