The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2018

Filed:

Apr. 15, 2014
Applicants:

Vib Vzw, Ghent, BE;

Katholieke Universiteit Leuven, K.u.leuven R&d, Leuven, BE;

Inventors:

Johan Thevelein, Blanden, BE;

Annelies Goovaerts, Putte, BE;

Françoise Dumortier, Blanden, BE;

Maria Remedios Foulquie-Moreno, Brussels, BE;

Steve Swinnen, Zichem, BE;

Thiago Martins Pais, Sinop, BR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/81 (2006.01); C12P 7/06 (2006.01); C07K 14/395 (2006.01);
U.S. Cl.
CPC ...
C12N 15/81 (2013.01); C07K 14/395 (2013.01); C12P 7/06 (2013.01); Y02E 50/17 (2013.01);
Abstract

The disclosure relates to a specific yeast allele of KIN3 that is involved in maximal alcohol accumulation and/or in tolerance to high alcohol levels. Preferably, the alcohol is ethanol. In a preferred embodiment, this specific allele is combined with specific alleles of ADE1 and/or VPS70. More specifically, the disclosure relates to the use of these alleles for the construction and/or selection of high alcohol tolerant yeasts, by stacking of positive alleles, or the selection and construction of low alcohol producing yeasts by stacking of negative alleles.


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