The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2018
Filed:
Jun. 04, 2014
Applicant:
Dsm Ip Assets B.v., Heerlen, NL;
Inventors:
Paul Klaassen, Echt, NL;
Paulus Petrus De Waal, Echt, NL;
Rene Marcel De Jong, Echt, NL;
Arnold Jacob Mattieu Driessen, Groningen, NL;
Jeroen Gerben Nijland, Groningen, NL;
Hyun Yong Shin, Groningen, NL;
Assignee:
DSM IP ASSETS B.V., Heerlen, NL;
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12P 19/34 (2006.01); C12N 15/00 (2006.01); C12N 1/00 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01); C07K 14/395 (2006.01); C12P 19/02 (2006.01);
U.S. Cl.
CPC ...
C07K 14/395 (2013.01); C12P 19/02 (2013.01);
Abstract
The invention relates to a polypeptide having one or more substitution at a position corresponding to position 339 or 376 of SEQ ID NO: 59, wherein the polypeptide is a member of the Major Facilitator Superfamily (MFS). In an embodiment, the substitution is at position corresponding to 376 and wherein the amino acid at that position is replaced by an amino acid that has a van der Waals volume of 80 to 138 Åand a side chain hydrophobicity of 10 to 100 Δt.