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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10000488 B1

PDFFull Text
Date of Patent:
Jun. 19, 2018

Filed:

Sep. 10, 2015

Heterocyclic compound

Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Satoshi Yamamoto, Kanagawa, JP;

Junya Shirai, Kanagawa, JP;

Tsuneo Oda, Kanagawa, JP;

Takashi Imada, Kanagawa, JP;

Mitsunori Kono, Kanagawa, JP;

Ayumu Sato, Kanagawa, JP;

Yoshihide Tomata, Kanagawa, JP;

Atsuko Ochida, Kanagawa, JP;

Naoki Ishii, Kanagawa, JP;

Yusuke Sasaki, Kanagawa, JP;

Yoshiyuki Fukase, New York, NY (US);

Tomoya Yukawa, Kanagawa, JP;

Shoji Fukumoto, Hyogo, JP;

Assignee:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Attorneys:

Anne M. Reynolds

Casimir Jones, S.C.

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 401/14 (2006.01); C07D 413/12 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 239/96 (2006.01); C07D 409/14 (2006.01); C07D 403/12 (2006.01); C07D 401/12 (2006.01); C07D 417/14 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 239/96 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract

The problem of the present invention is to provide a compound having a superior RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.

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