Davisco Foods International, Inc.

Devisco Foods International, Inc.

Yves Pouliot

Martin E Davis

Anand Rao

Sylvie Gauthier

Line Gourley

Anne-Francoise Allain

Enzymatic digests of whey protein concentrates were prepared using animal, bacterial and fungal proteases, and evaluated for antihypertensive activities. The highest ACE-inhibitory activity was obtained with the purified peptide &#x3b2;-1g (f142&#x2013;148) obtained by chemical synthesis, for which an ICvalue of 0.04 mg powder.mlwas found. The hydrolysates derived from BiPRO&#x2122; whey protein isolate and &#x3b2;-1g both gave higher antihypertensive activities (ICvalues of 0.29 to 0.90 mg powder.ml) than the other hydrolysates tested (ICvalues of 0.96 and 1.30 mg powder.ml). The recovered hydrolysate can be used to treat hypertension in mammals such as humans and domestic pets such as dogs and cats.

Enzymatic treatment of whey proteins for the production of antihypertensive peptides and the resulting products

Enzymatic digests of whey protein isolates were prepared using animal, bacterial and fungal proteases, and evaluated for antihypertensive activities. The antihypertension activity was obtained with a hydrolysate of whey protein isolate prepared with a porcine trypsin. The recovered hydrolysate is used to treat hypertension in mammals such as humans and domestic pets such as dogs and cats.

Treatment of hypertension in mammals with hydrolyzed whey proteins

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Charny, Canada

Yves Pouliot