National Institute of Advanced Industrial Science and Technology

Rion Company Ltd.

Kioxia Corporation

Yusuke Matsuura

Haruhisa Kato

Ayako Nakamura

Kaoru Kondo

Takuya Tabuchi

Hidekazu Hayashi

Kazuna Bando

Hiroshi Tomita

For an easy calibration using calibration particles, provided is a measuring device to capture images of target objects. An image analyzer acquires multiple images obtained at a predetermined time interval, (a) specifies the mean-square displacement of a bright point of a calibration particle based on the displacement of the bright point of the calibration particle in the multiple images in a calibration mode, and (b) specifies the mean-square displacement of a bright point of the target particle based on the displacement of the bright point of the target particle in the multiple images in a measurement mode. A particle size analyzer (c) derives the particle size of the target particle from the mean-square displacement of the bright point of the target particle based on the mean-square displacement of the bright point of the calibration particle and the particle size of the calibration particle in an analysis mode.

Particle measuring device, calibration method, and measuring device

The purpose of the present invention is to provide a particulate observation device using light scattering, which includes a means for determining the three-dimensional position of a particle, and can measure an accurate particle size or impart various properties of same. The present invention is characterized by including a position determination means which captures, with an optical microscope, an image of light scattered from particles in a dispersion medium to which laser light is emitted, and determines a three-dimensional position of each particle from the obtained two dimensional image, wherein the position determination obtains two-dimensional coordinates along the two-dimensional image from luminescent point positions of the particles, and determines the depth position along a coordinate axis vertical to the two-dimensional image from the diameters of diffraction fringes of the luminescent points.

Particulate observation device and particulate observation method

A measuring method enabling simple and accurate measurement of a flow velocity distribution in a flow field inside a flow passage of an optical cell and a particle size-measuring method using the measuring method are provided. Providing a tracer particle of a smaller size than wavelength &#x3bb; of laser light into the flow passage and capturing a bright spot attributed to light scattering from tracer particles by camera, and obtaining the flow velocity distribution by the analysis unit by obtaining an amount of movement of each tracer particle from movement of the bright spot and correcting a Brownian motion component from a correlation between an average value of variations of the amount of movement and Brownian motion are performed.

Flow velocity distribution measuring method and particle size measuring method

Provided is a particle measuring device and a particle measuring method for measuring a particle size with favorable accuracy. A flow cell () includes a flow passage () of sample fluid. An irradiation optical system () irradiates, with light from a light source (), the sample fluid in the flow passage (). An imaging unit () captures, from an extension direction of the flow passage (), an image of scattered light from the particle in a detection region in the flow passage (), the light passing through the detection region. A particle size specifying unit specifies a movement amount of the particle in a two-dimensional direction by Brownian motion based on multiple still images of a particle image captured at a predetermined frame rate by the imaging unit (), thereby specifying the particle size of the particle from the movement amount in the two-dimensional direction.

Growing community of inventors

Tsukuba, Japan

Yusuke Matsuura