Usv Pharmaceutical Corporation

Kraft General Foods, Inc.

General Foods Limited

Kraft Foods, Inc.

Rorer Pharmaceutical Corporation

Thomas D Lee

Robert W Wood

Richard E Brown

Fu-chih Huang

Rohit M Desai

Ernest Magnien

Raymond Youssefyeh

William J Dell

Anne M Addesso

Utpal Chakraborty

Madeline M Bissonnette

Wan-kit Chan

David J Barnard

Ready-to-drink, aspartame-sweetened beverages having longer shelf-life are prepared by raising the pH of the beverage to above 3.2 while maintaining a sour taste which is equivalent to a beverage having a pH of 2.9. The beverage of this invention are formulated with a citric acid to citrate buffer salt ratio (by weight) of 2.5-4.3:1.

Ready-to-drink, aspartame-sweetened beverages

A chocolate yogurt containing active cultures and having a diminished acid taste compatible with chocolate and a new product form that enables the enjoyment of the product utilizing only normal channels of distribution are enabled by separately preparing and packaging a yogurt base portion and a chocolate flavoring portion. The yogurt base portion contains active cultures and has a pH of less than about 4.6. The chocolate flavoring portion containing cocoa, nonfat dry milk solids, and a buffering salt. The two portions are packed, preferably, in a two-piece composite package. The two packages are opened and the contents mixed just prior to consumption.

Chocolate yogurt and preparation

Fruit-flavored, powdered gelatin dessert mixes are formulated to obtain a relatively high pH of at least 4.15, and a relatively low gelatin load weight while still retaining a desirable sour taste. The mix contains adipic acid and fumaric and/or citric acid at a weight ratio of 15-21:1. The mix also contains soluble sodium buffer salts and soluble citrate buffer salts at a weight ratio of 0.9-2:1.

Gelatin gels and powdered mixes therefor

An edible salt enhancing composition is provided which is a combination of L-aspartic acid and L-arginine and sodium chloride.

Seasoned food product with a salt enhancer

Salt enhancer

Quinolinyl ether or thioether tetrazoles as agents for the treatment of

Compounds of the formula: ##STR1## and salts thereof, wherein,

Styryl tetrazoles and anti-allergic use thereof

This present invention provides an improved method for producing N-L-aspartyl-D-alanine fenchyl ester or N-L-aspartyl-methylalanine fenchyl ester and new compositions of fenchol derivatives which are intermediate compositions in the preparation of the above described fenchyl esters.

Process for the preparation of N-L-aminodicarboxylic acid esters and new

Indolyl dieneoic acids and esters are disclosed possessing valuable pharmaceutical activity, particularly as lipoxygenase inhibitors with anti-inflammatory and anti-allergic properties.

Indolyl compounds and hyposensitivity use thereof

Provided are compounds of the structure: ##STR1## wherein R.sub.1, R.sub.3, R.sub.5 and R.sub.6 are independently H, alkyl, aralkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkenyl, alkynyl, hydroxy, hydroxyalkyl, alkoxy, mercapto, mercaptoalkyl, alkylthio, amino, alkylamino, aminoalkyl, formyl, carboxy and salts thereof, carbalkoxy, alkanoyl, cyano, nitro, halo, trifluoromethyl, alkylsulfonyl, aminosulfonyl, carbamoyl or cycloalkyl; and

7,8-Dihydroimidazo[1,5-a]pyrazin-8-ones

A pharmaceutical composition containing a therapeutically effective amount of a pyridinylimidazole 4- or 5-substituted carboxylic acid and esters thereof is provided to treat cardiovascular ailment.

Pyridinylimidazole pharmaceutical composition

Provided are imidazoquinoxalines of the structures: ##STR1## wherein R.sub.1, R.sub.5, R.sub.6 and R.sub.7 are independently H, alkyl, aryl, alkenyl, alkynyl, hydroxy, hydroxyalkyl, alkoxy, mercapto, mercaptoalkyl, alkylthio, amino, alkylamino, aminoalkyl, carboxaldehyde, carboxylic acid and salts thereof, carbalkoxy, alkanoyl, cyano, nitro, halo, trifluoromethyl, alkylsulfonyl, sulfonamido, or R.sub.1, R.sub.5, R.sub.6 and R.sub.7 may be taken together with the adjacent group to form a methylenedioxy group. R.sub.4 is H, alkyl, alkenyl, alkynyl, aryl, aralkyl, hydroxy or alkanoyl. R.sub.3 is H, cyano, tetrazolo, carboxaldehyde, hydroxyalkyl, carboxylic acid and salts thereof or derivatives thereof such as esters or amides in which the substituent on the ester oxygen or amide nitrogen is alkyl, aryl, hydroxyalkyl, alkoxyalkyl or amino alkyl. R.sub.2 and R.sub.8 are independently H, alkyl, aryl, halo, amino, alkylamino, arylamino, hydroxyamino, hydroxy, alkoxy, mercapto or alkylthio, and X is oxygen, sulfur, imino, and hydroxyimino.

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Scarsdale, NY, United States of America

Thomas D Lee