Cpc International, Inc.

Shigehiro Enokizono

Soichiro Ushiro

Norio Kamata

Sakado Kanno

Sumiko Kanno

Glucose isomerase is immobilized in an active form by adsorbing the glucose isomerase onto a colloidal silica. The enzyme is contacted with the colloidal silica and the resulting composite solidified by freezing. Optionally, the composite may be gelatinized prior to freezing. The composite is then used for the isomerization of glucose to fructose.

Process for immobilizing glucose isomerase and a method of continuous

A dextrose containing solution is treated with chelating resin capable of removing heavy metals and thereafter at least a part of the dextrose is isomerized to levulose in the presence of a dextrose isomerase enzyme preparation.

Starch hydrolysate having less than 5 ppm of heavy metals

Process for immobilizing glucose isomerase

Method of treating a dextrose solution

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Ageo, Japan

Shigehiro Enokizono