Bioject Inc.

Bioject Medical Technologies, Inc.

Other

Vitajet Corporation

Amgen Inc.

Path, Inc.

Sergio Landau

Daniel E Williamson

James Michael Bonicatto

John R Marshall

Robert A Miller

John Lawrence Staylor

Robert B Hubler

John Stiggelbout

Timothy J Salo

John L Staylor

Glenn D Austin

Ryan R Beylund

Christopher F Sautter

Keith K Daellenbach

T Patrick Lennon

Roger Liu

Theodore Walaka Sedler

Eric W Logvin

Dan Williamson

Brandon Law

A manual brewing press with a lever assembly including a post, a base, a press plate extending from the post, and an elongated lever with an attached lever hook. A brew head is configured to be inserted into a top of the press plate and comprises a cylinder and a piston with a plunger disposed inside the cylinder and a stem integrating a pressure gauge. A sealing element is disposed adjacent to at least one of the stem and the plunger. A portafilter attaches to the press plate underside. The lever hook engages the stem of the piston, moves the plunger down and up inside the cylinder as the elongated lever is lowered and raised respectively, pushing water inside the cylinder down through coffee grounds in the portafilter when the elongated lever is lowered, and pulling the plunger back up when the elongated lever is raised for a subsequent brewing.

Manual brewing press with lever hook and method of operating the same

This invention provides a novel solution for a device and method including a hand-operated brewing pressand a separate brewing containerconfigured to brew a beverage. The beverage is brewed via the hand-operated brewing pressby first attaching the portafiltercontainer a portion of the pre-ground brewing medium onto a press plate. Next, the cylinder is attached onto the portafilter. Next, a portion of hot fluidis poured into the cylinder. Next a pistonis inserted into the cylinder. Next, a force is applied to the leverresulting in the pistonsliding downward inside the cylinder applying a pressure to the portion of hot fluid, the portion of hot fluidis forced to flow into the portafilterand through the portion of the pre-ground brewing mediumto produce the brewed beverage.

Manual brewing press

This invention includes a cart assembly with an integrated cooler and a configurable and expandable cargo platform. The cart assembly comprises a chest compartment. One end of support beams is attached to the front surface of the chest. The opposite ends of the support beams are attached to the rear surface of the extension member. One end of an expanding platform is attached to the front surface of the chest. The opposite end of the expanding platform is attached to the rear surface of the extension member. Ends of the telescoping support rails are attached on both the left and right sides of the chest. Opposite ends of the telescoping support rails are attached on both the left and right side of the extension member. The cart assembly can expand and collapse to accommodate larger or smaller cargos and reconfigure the platform into a table.

Configurable cart

Embodiments herein provide a kick scooter comprising of 4 main assemblies: a center deck, a front wheel assembly, a rear wheel assembly, and a handle assembly, where these 4 assemblies have means to be easily and quickly separated from, and attached to, each other. The scooter allows the user to collapse the whole scooter into a compact volume so that it can be carried in a small backpack and be able to be reassembled for use in a few seconds and without any tools.

Kick scooter

A gas-powered, single-use, needle-less hypodermic jet injection device includes a hand-held injector, and a drug injection cartridge which provides a cylinder of liquid medication to be injected, an injection orifice, and an injection piston. Forceful movement of the injection piston in the cylinder causes an injection jet of medication to be expelled from the injection orifice. The injection device also includes a hermetically sealed gas pressure capsule which remains sealed until the moment of injection and powers the jet injection after opening of this cartridge.

Single-use needle-less hypodermic jet injection apparatus and method

Needle-free injection devices and drug delivery systems are disclosed. The needle-free injection devices may include a drug delivery system, a power source, an activation system, and a disabling element. The drug delivery system may include a needle-free syringe and a drug storage system. The needle-free syringe may include a plunger slidably disposed within an injection chamber. The injection chamber may include an injection orifice, and the plunger may be configured to expel a volume of fluid from the injection chamber through the injection orifice. The drug storage system may include a storage chamber and an outlet. The drug storage system may be frangibly connected to the needle-free syringe with the outlet proximate to and fluidly connected with the injection orifice. The drug storage system may be configured to inject a fluid from the storage chamber through the outlet, through the injection orifice, and into the injection chamber.

Needle-free injection devices and drug delivery systems therefor

A needle-free injection device in which a gas cartridge or other source of pressurized gas is used to advance a piston and forcibly expel injectable fluid out through an injection orifice. When a gas cartridge is used, the gas cartridge may be moveable from an initial position to an actuating position in which gas is released to drive the injection, and a recoil inhibiter may be employed to prevent the gas cartridge from moving back to the initial position. A gas cartridge seal may be disposed on the gas cartridge and moveable with the gas cartridge to seal the gas cartridge against an interior wall of a gas cartridge housing. The needle-free injection device may also be configured so that sealing is compromised upon full advancement of the piston, so as to de-pressurize the device after delivery of an injection.

Needle-free injection system

A needle-free injection device, including a plunger and a spring operatively coupled with the plunger. The plunger is slidably disposed within a fluid chamber, is retractable to draw injectable fluid into the fluid chamber through an injection orifice, and may be advanced within the fluid chamber to forcibly eject injection fluid out through the injection orifice. The spring is configured to be compressed during arming of the injection device, and decompressed during discharge to forcibly advance the plunger within the fluid chamber. The injection device further includes an actuator operable to cause the spring to be compressed during arming of the injection device, and selectively operable prior to decompression of the spring to cause the plunger to be moved to a desired position within the fluid chamber.

Spring powered needle-free injection system

A needle-free injection device is described. The injection device includes a user-grippable housing and a syringe assembly movably secured to the housing. The syringe assembly is configured to expel injectable fluid out of a nozzle upon application of pressurized gas to the syringe assembly. The injection device also includes a pressurized gas delivery mechanism disposed within the housing and configured to selectively apply pressurized gas to the syringe assembly. The pressurized gas delivery mechanism is at least partly actuated by pressing the nozzle onto an injection site so that the syringe assembly moves relative to the housing.

A needle-free injection device is described. The injection device typically includes a system for providing directed and pre-selected pressure and a nozzle with an orifice for defining a stream of fluid that is directed toward the skin of a patient against which a front end of the nozzle is positioned. The device also normally includes an engagement system that can selectively engage the nozzle with the pressurizing system so that the nozzle can be mounted to the pressurizing system to receive pressure for injection and so that after injection the nozzle can be removed and replaced for each new use of the device.

High workload needle-free injection system

A needle-free injection device capable of delivering pressurized injections to an injection site. The device may include a barrier dispenser configured to provide a disposable piece of barrier material for each injection, so as to reduce risk of cross-contamination. The device may also include various sensors, a firing disable mechanism, a multiple use and/or disposable fluid path, and/or other mechanisms configured to enhance sterility and prevent contamination.

A method and apparatus for providing high throughput injections is provided. The invention provides a filling device adapted to deliver injectate from a common reservoir to a plurality of disposable fluid injection assemblies and a reusable propulsion assembly adapted to receive a filled disposable fluid injection assembly and deliver an injection to a patient.

A method of manufacture for a drug cartridge assembly. The method includes providing a drug cartridge, providing a nozzle sub-assembly, and sterilizing the drug cartridge and nozzle sub-assembly. The method further includes assembling the drug cartridge and nozzle sub-assembly together in a configuration that enables ejection of liquid out of the drug cartridge through the nozzle sub-assembly. The method further includes filling the drug cartridge with a liquid, such as an injectable drug. The method may include separate sterilization of the drug cartridge and nozzle sub-assembly, using different sterilization processes. Portions of the method may be performed prior to sterilization within a first cleanroom, with subsequent steps being performed in a second cleanroom having a substantially lower particulate-per-volume rating than the first cleanroom.

Drug cartridge assembly and method of manufacture

A needleless injector system including: a first injector assembly; a gas capsule disposed within the first injector assembly and containing pressurized gas, with a pierceable surface at the forward end thereof to provide an injection source; a gas capsule piercing member disposed within the first injector assembly, where the piercing member and the gas capsule are movable relative to each other; a second injector assembly containing a medical treatment fluid and having a forward facing injection orifice for injecting the medical treatment fluid into a patient; and a resilient seal mounted between the gas capsule and the first injector assembly to contain all pressurized gas within a forward end of the first injector assembly after pressurized gas is released from the gas capsule following piercing of the gas capsule, in order to cause an immediate increase in pressure in the medical treatment fluid contained within the second injector assembly.

A gas-powered, durable, needle-less hypodermic jet injection device ( ) includes a hand-held injector ( ) which receives into an injection cylinder a volume of liquid medication to be injected in the form of a high velocity jet capable of penetrating the skin without the use of a hypodermic needle. The injection device provides an injection orifice, and an injection piston. Forceful movement of the injection piston causes a high velocity injection jet of liquid medication to be expelled from the injection cylinder via the injection orifice. The injection device includes features which improve its usability, particularly for users with hands that are possibly weak, feeble, or arthritic, for example; and also includes additional features which improve manufacturability, durability, and cost effectiveness of the device.

Growing community of inventors

Laguna Niguel, CA, United States of America

Sergio Landau