The Nutrasweet Company

Baxter International Inc.

Baxter Healthcare Sa

Run Wang

Richard J Johnson

Clifford J Holmes

Steve A Schroeder

Cliff Holmes

Valerie Leesch

Stephen A Schroeder

Subbaroa V Ponakala

Vinod Chaudhary

Richard Johnson

Clifford Holmes

John Lamela

Line Skoufos

Methods of treating a dialysis component by providing a dialysis component and contacting the dialysis component with an enzyme are provided. The enzyme breaks down microbial contaminants in the dialysis component. The enzyme may be separated from the dialysis component to provide a purified dialysis component. The purified dialysis component may be substantially free of microbial contaminants that cause a cytokine response in humans.

Destruction of microbial products by enzymatic digestion

This invention provides a method for preparing a liquid composition of N-[N-(3,3-dimethylbutyl)-L-&#x3b1;-aspartyl]-L-phenylalanine 1-methyl ester comprising the steps of (a) providing a liquid carrier; and (b) mixing N-[N-(3,3-dimethylbutyl)-L-&#x3b1;-aspartyl]-L-phenylalanine 1-methyl ester with said liquid carrier in a ratio of up to 3:2 by weight to produce a liquid composition. The resulting liquid composition would be capable of fully dissolving or suspending neotame and may be mixed with or added to a food or beverage product in an amount effective to sweeten the food or beverage product. This invention is also directed to the novel liquid compositions prepared by the process of this invention and to the food and beverage products sweetened thereby. The liquid carriers of this invention include water, alcohol and mixtures thereof.

Method of preparing liquid compositions for delivery of N-[N- (3,3-dimethylbutyl-L-&#x3b1;-aspartyl]-L-phenylalanine 1-methyl ester in food and beverage systems

A novel amorphous N-&lsqb;N-(3,3-dimethylbutyl)-L-&agr;-aspartyl&rsqb;-L-phenylalanine 1-methyl ester compound is disclosed. Also disclosed are processes for preparing the compound. The novel compound has improved solubility and dissolution properties compared to the known monohydrate.

Amorphous N-&lsqb;N-(3,3-dimethylbutyl)-L-&agr;-aspartyl&rsqb;-L-phenylalanine 1-methyl ester

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Gurnee, IL, United States of America

Run Wang