Abbott Laboratories Corporation

University of Tennessee Research Foundation

New England Deaconess Hospital Corporation

Michael Donald Karlstad

Bruce R Bistrian

Stephen Joseph Demichele

Edward Anthony Mascioli

There is disclosed structured lipid containing either a gamma-linolenic acid or a dihomogamma-linolenic acid residue, together with an n-3 fatty acid residue and a medium chain fatty acid residue on the same glycerol backbone. This structured lipid is particularly well adapted to the treatment of disease or stress states. The gamma-linolenic or dihomogamma-linolenic acid residues modify the prostanoid synthesis pathway, reducing the level of series '2' prostanoids and elevating the levels of series '1' and '3' prostanoids. The n-3 fatty acid residue enhances the level of series '1' prostanoids as well as increases the production of series '3' prostanoids. The medium chain fatty acid residues enhances the absorption of the structured lipid. There is also disclosed enteral and parenteral diets as well as nutritional supplements containing the structured lipids of the invention.

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Knoxville, TN, United States of America

Michael Donald Karlstad