Rensselaer Polytechnic Institute

Mengzhou Li

Ge Wang

Wenxiang Cong

David S Rundle

Zheng Fang

In one embodiment, there is provided a micro-CT (computed tomography) apparatus. The micro-CT apparatus includes an x-ray source coupled to a source robotic arm, an x-ray detector coupled to a detector robotic arm, and a computing device. The computing device includes a data acquisition module and a reconstruction module. The data acquisition module is configured to acquire local scan data of a volume of interest (VOI) contained in an imaging object. The reconstruction module is configured to reconstruct an image of the VOI based, at least in part, on the local scan data, and based, at least in part, on background compensation data.

Robotic arm-based clinical micro-CT system and method

A method for x-ray photon-counting data correction. The method includes generating, by a training data generation module, training input spectral projection data based, at least in part, on a reference spectral projection data. The training input spectral projection data includes at least one of a pulse pileup distortion, a charge splitting distortion, and/or noise. The method further includes training, by a training module, a data correction artificial neural network (ANN) based, at least in part, on training data. The data correction ANN includes a pulse pileup correction ANN, and a charge splitting correction ANN. The training data includes the training input spectral projection data and the reference spectral projection data.

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Troy, NY, United States of America

Mengzhou Li