Mars, Incorporated

Matthew Ronald Gibbs

Scott Joseph McGrane

Richard Masten Fine

Boris Klebansky

Andrew John Taylor

Jerry Wallace Skiles

Stephen James Harris

Carlos Juan Hernangomez De Alvaro

Matthew Coates

Scott Jospeph Mcgrane

Scott Mcgrane

Scott Joseph Mcgrane

Neil George Desforges

A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a GPR92 receptor that can be used to enhance palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.

Compounds that modulate GPR92 receptor activity and pet food products containing the same

A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a GPR120 fatty acid receptor that can be used to enhance the fatty acid taste and/or palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.

Compounds that modulate fatty acid receptor activity and pet food products containing the same

The presently disclosed subject matter relates to methods of screening raw materials and pet food products to manufacture a palatable pet food product. The presently disclosed subject matter also relates to methods for identifying compounds that modulate the activity and/or expression of a taste receptor.

Screening methods using GPRC6A taste receptors and pet food products and compositions prepared using the same

The present invention relates to an assay for use in a method of determining the oral health status of a canine animal by identifying certain bacteria present or absent in a sample taken from the animal, and applying the information set out herein for each identified bacteria to statistical models in order to determine the oral health status of the animal.

Assay and method

The present disclosure provides methods for identifying compounds that modulate the activity and/or expression of GPR92, wherein said compounds can be incorporated into flavor compositions that can be used to modify the taste and/or palatability of pet food products. In certain non-limiting embodiments, the present disclosure provides a method for identifying a composition that modulates the activity of a GPR92 receptor comprising (a) contacting a test agent with a GPR92 receptor, (b) determining the activity of the GPR92 receptor, and (c) selecting as the composition, a test agent that increases the activity of the GPR92 receptor.

Methods for identifying modulators of GPR92

The presently disclosed subject matter relates to methods of screening raw materials and pet food products to manufacture a palatable pet food product. The presently disclosed subject matter also relates to methods for identifying compounds that modulate the activity and/or expression of an olfactory receptor.

Screening methods using olfactory receptors and novel compounds identified using the same

Amino acids present in domains of an umami taste receptor are described herein, wherein the amino acids interact with at least one nucleotide derivative and/or at least one transmembrane compound that potentiates, modulates, increases, and/or enhances the activity of the umami receptor. Such compounds can be used in flavor compositions to enhance the umami taste and/or palatability of food products.

Methods for modulating taste receptors

Methods for identifying compounds that modulate the activity and/or expression of a calcium-sensing receptor, wherein said compounds can be incorporated into flavor compositions that can be used to modify the kokumi taste and/or palatability of pet food products.

Methods for identifying modulators of calcium-sensing receptors

The present invention relates to a method of identifying a compound that binds to or modulates the activity of one or more polypeptides encoding one or more receptors that are involved in the detection and perception of fatty acids.

Growing community of inventors

Leicestershire, United Kingdom

Matthew Ronald Gibbs