Nestec S.a.

Lionel Bovetto

Catherine Mace

Denis Breuille

Matthieu Pouzot

Sandrine Gremlich

Rodolphe Fritsche

Francoise Maynard

Joerg Hau

Sophie Pecquet

Etienne Pouteau

Trent Stellingwerff

Daniel Moore

Christophe JE Schmitt

Frédéric Robin

The present invention relates to a milk fraction obtainable by acidification of micellar casein and separation from precipitated casein named acid soluble protein from micellar casein. It was found that the milk fraction and especially certain sub-fractions thereof are bioactive and promote GLP-1 release in vitro. Based on these results, acid soluble protein from micellar casein may be useful in the treatment and the prevention of diabetes type II, obesity and may further be added to formulas directed at other purposes addressing the gastro-intestinal tract.

Acid soluble proteins from micellar casein

The present invention pertains to nutritional and pharmaceutical compositions for treating and preventing cyclooxygenase-2 mediated diseases and to a process for increasing the cyclooxygenase-2 inhibiting activity of a product. In addition thereto, the present invention relates to the use of one ore more milk protein fractions and/or one ore more milk protein preparations for inhibiting the activity of cyclooxygenase-2 (COX-2), in particular for the preparation of a medicament or a functional food for treating and preventing cyclooxygenase-2 mediated diseases.

Milk fractions and milk preparations for treating and/or preventing COX-2 mediated diseases

A hypoallergenic composition for the induction of protein tolerance in at risk individuals of protein allergy. The composition contains (i) a &ldquo;non allergenic&rdquo; protein extensively hydrolyzed basis and/or of (ii) a free amino acid basis. The composition contains, as an active ingredient, at least one tolerogenic peptide of the allergenic protein.

Hypoallergenic composition containing tolerogenic peptides

Growing community of inventors

Larringes, France

Lionel Bovetto