National Health Research Institutes

Materials Analysis Technology (US) Corp.

Lin-ai Tai

Chih-hsun Chu

Yong-fen Hsieh

Yu-feng Ko

Pradeep Sharma

Chung-shi Yang

Yu-ching Chen

Hsiao-chun Ting

A TEM specimen kit is disclosed, which comprises: (a) a top substrate and a bottom substrate, the top and the bottom substrates being transparent and substantially parallel to each other; (b) a first spacer and a second spacer, located beneath the top substrate and sitting on the bottom substrate, the second spacer being opposite to and spaced apart from the first spacer at a distance of d; and (c) a chamber formed between the top and bottom substrate and between the first and second spacer, the chamber having two ends open to the atmosphere and characterized by having a height defined by the thickness h of the spacer, wherein the height being smaller than the diameter of a red blood cell. Also enclosed are methods for preparing a dry specimen for TEM nanoparticle characterization, and methods for analyzing TEM images of nanoparticles in a liquid sample.

Specimen preparation for transmission electron microscopy

Growing community of inventors

Zhunan, Taiwan

Lin-ai Tai