Ajinomoto Co., Ltd.

Keiko Noguchi

Mika Moriya

Miku Toyazaki

Mikhail Markovich Gusyatiner

Benjamin Mijts

Elvira Borisovna Voroshilova

Tatyana Viktorovna Leonova

Keita Fukui

Sayaka Asari

Dmitriy Vladimirovich Filippov

Christine Roche

Yuri Nagai

Yuri Uehara

Rekha Murali

A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism that is able to produce the objective substance, which microorganism has been modified so that the activity of an enzyme involved in SAM cycle (SAM cycle enzyme) is increased.

Method for producing objective substance

A method for producing of an L-amino acid is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been modified so that the acpP-fabF operon is attenuated, in a medium, and collecting the L-amino acid from the medium or cells of the bacterium.

Method for producing L-amino acid

The present invention provides a method for producing L-amino acids, such as L-arginine, L-citrulline, and L-lysine, using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genusor, which has been modified to attenuate expression of one or more genes, such as the pepA, pepB, and pepD genes.

Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family, having attenuated expression of gene(s) encoding peptidase

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Kanagawa, Japan

Keiko Noguchi