Ajinomoto Co., Ltd.

Tokyo Institute of Technology

Kazuteru Yamada

Hideo Hosono

Hiroyuki Kojima

Toshiharu Yokoyama

Michikazu Hara

Masaaki Kitano

Hiromi Noguchi

Mitsuhiro Kishino

Toru Numaguchi

Munenobu Ito

Yoshihiko Hara

Kenji Abe

Ryo Takeshita

Yousuke Nishio

Yuri Uehara

Kosuke Yokota

Youko Yamamoto

Ye Zhang

Chika Hikichi

Naoki Iwanaga

Yasuhiro Oota

Provided is a novel production system that does not involve, or can minimize, the transport of liquid ammonia in the production of an organic compound or the production of a microorganism by microbial fermentation. A production system for an organic compound or a microorganism includes: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported ruthenium catalyst; and a culture apparatus that cultures a microorganism having organic compound productivity using ammonia originating from the ammonia-containing gas obtained by using the ammonia synthesis apparatus.

Production system and method of production for organic compound or microorganism

A method for producing an L-amino acid such as L-lysine is provided. An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability, which has been modified so that the activity of a carotenoid biosynthesis enzyme is increased, in a medium, and collecting the L-amino acid from the medium.

Method of producing an l-amino acid involving a carotenoid biosynthesis enzyme

A production system for a product selected from a nitrogen-containing product and a fermented and cultured product that does not involve (or can minimize) the transport of liquid ammonia can include: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported metal catalyst containing as a support one or more selected from the group consisting of: i) a conductive mayenite compound; ii) a two-dimensional electride compound or a precursor thereof; and iii) a complex formed of a support base containing at least one metal oxide selected from ZrO, TiO, CeO, and MgO and a metal amide represented by a formula M(NH)(where M represents one or more selected from Li, Na, K, Be, Mg, Ca, Sr, Ba, and Eu; and x represents a valence number of M) supported by the support base.

Production system and method of production for product selected from nitrogen-containing product and fermented and cultured product

A method for producing a target substance is provided. A target substance is produced by culturing a coryneform bacterium, which is able to produce a target substance, and which also has an improved ability to assimilate xylose as a result of the introduction of a mutation into a coding region and/or an expression control region of the NCgl2954 gene on the chromosome of the bacterium. The culture is conducted in a medium containing xylose, and the target substance can be collected from the medium.

Method for producing target substance

A target substance can be produced by culturing a bacterium having an ability to produce 2-ketoglutaric acid or a derivative thereof, and an ability to produce xylonic acid from xylose, which is imparted with xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or in which these activities are enhanced, in a medium containing xylose as a carbon source to produce and accumulate the target substance in the medium, and collecting the target substance from the medium.

Method for producing a target substance by fermentation

Growing community of inventors

Kanagawa, Japan

Kazuteru Yamada