Mitsui Norin Co., Ltd.

Kazuo Okushio

Yukihiko Hara

Hajimu Yamamoto

Kanzo Sakata

Hajime Asai

Tadashi Kitamikado

Kozo Nakamura

A glycoside of inositol which has been isolated from a hot-water extract of tea leaves. The glycoside is identified from the analytical results to be 2-O-beta-L-arabinopyranosyl-myo-inositol.

Inositol glycoside 2-O-Beta-L-arabinopyranosyl-myo-inositol

Extract of tea leaves or (-)-epigallocatechin gallate as the principal ingredient of the extract forms a complex with active aluminum hydroxide. The animal test using rats has established that these complexes have therapeutic effect for gastric ulcers, e.g. pylorus-ligated ulcer and indomethacin-induced ulcer, when orally administered. Tests were also undertaken for the effect on the secretion of gastric juice and acute toxicity of these complexes using rats and mice as the test animals.

Complex of tea-leaf extract and active aluminum hydroxide

Growing community of inventors

Shizuoka, Japan

Kazuo Okushio