University of Florida Research Foundation, Incorporated

Xhale, Inc.

Afroparistech

Jon Dale Stewart

Donn Dennis

Richard Joel Melker

Christopher D Batich

Charles R Martin

Matthew M Booth

Florent Allais

David G Bjoraker

Richard J Rogers

Susan Kim Boehlein

Bradford T Sullivan

Louis Michel Marie Mouterde

John Frederick Horn, Jr

Larkin Curtis Hannah

Ronald E Youngblood

Janine R Shaw

The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (S)-&#x3b3;-hydroxymethyl-&#x3b1;,&#x3b2;-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the invention comprises alkene reduction of a target compound by reacting the compound with an Old Yellow Enzyme (OYE) that reduces alkene bonds. In one embodiment, the OYE is OYE 2.6 fromand comprises the amino acid sequence of SEQ ID NO: I. In a specific embodiment, the enzyme is an Old Yellow Enzyme (OYE) 2.6 mutant having an amino acid substitution at position 78 in the sequence, wherein the tyrosine at position 78 is substituted with a tryptophan amino acid (Y78W) and is designated as OYE 2.6 Y78W (SEQ ID NO:2).

Materials and methods for alkene reduction of levoglucosenone by an alkene reductase

Compositions and methods for increasing heat resistance or starch biosynthesis in plants are provided herein. Polynucleotides, polypeptides, and expression constructs for expressing mutant AGPase subunit proteins, plants comprising the polynucleotides, polypeptides or expression constructs, and methods of producing transgenic plants are also provided.

Methods for increasing grain yield

The present invention provides systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments of the invention, electrochemical- or coulometric-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose.

Condensate glucose analyzer

The invention relates to the nanotubes of various sizes and composed of a wide variety of materials, or combination of materials. The invention also describes the use of such nanotubes for the delivery of various payloads and, in particular, for the in vivo delivery of bioactive substances.

Nanoparticle delivery system

Growing community of inventors

Gainesville, FL, United States of America

Jon Dale Stewart