Jiangnan University

Infinitus (china) Company Ltd.

Wuxi Huashunminsheng Food Co. Ltd.

Anjoy Foods Group Co., Ltd.

Hubei Anjoy Food Co. Ltd.

Nanjing Xianou Instruments Manufacture Co., Ltd

Sichuan Anjoy Food Co. Ltd.

Henan Anjoy Food Co. Ltd.

Jianxin Zhao

Hao Zhang

Gang Wang

Qixiao Zhai

Fengwei Tian

Wenwei Lu

Daming Fan

Yongquan Chen

Bowen Yan

Haiqin Chen

Zhennan Gu

Qiuxiang Zhang

Yuanda Song

Huayu Yang

Bo Yang

Wei Feng Chen

Yuanyuan Wang

Fangli Ma

Jianlian Huang

Wenhua Gao

Xiaoming Liu

Shumao Cui

Wei Chen

Qian Chen

Junyong Xiao

Leilei Yu

Yejun Wu

Huizhang Lian

Meiyi Zhang

Xiaofeng Zhu

Zilong Zhao

Hongwei Cao

Huizi Tan

Chung Wah Ma

Kai Wang

Minghua Hu

Lingyun Xiao

Jiangping Chen

Xuepeng Li

Xin Tang

Chao Chen

Bowen Wang

Nana Zhang

Liming Jin

Zhongliang Hu

Peijun Tian

Feifei Chi

Zhexin Fan

Xi Liang

Qingmin Kong

He Gao

Jun Cao

Wenguo Zhou

Haiqun Chen

Xidong Jiao

Dongna Ruan

Dengying Lei

Qingmiao Zhang

Tenghui Yu

Eryin Wang

Feng Hang

Darning Fan

Siyi Fang

Wenli Huang

Xiuxiu Li

Yin Zhang

Shunhe Wang

Xinyang Liu

Jinbiao Fei

Guangsu Zhu

Ke Pang

Guangfei Hao

Zhifeng Fang

Min Guo

Wenhai Zhang

Weijian Ye

Xiaoyun Huang

Xing Jin

Kai Du

Yuhao Zhang

Shanshan Zhao

Bingyong Mao

Wanqing Xu

The disclosure disclosesCCFM6432 for alleviating depression, food fermented thereby and application thereof. TheCCFM6432 of the disclosure can be used to prepare food, health-care products and drugs with the functions of resisting depression, resisting inflammation, resisting inflammatory bowel disease, resisting obesity and resisting type I diabetes. The disclosure further provides fermented food. The fermented food is produced by fermentation using theCCFM6432, and the fermented food includes solid food, liquid food, and semi-solid food. TheCCFM6432 has very broad application prospects.

Pediococcus acidilactici CCFM6432 for alleviating depression, food fermented thereby and application thereof

The present disclosure discloses a strain ofcapable of preventing and/or treating periodontitis and an application thereof, belonging to the field of microbiology technology. The present disclosure has screened to obtain a strain ofCCFM1139. TheCCFM1139 can alleviate periodontitis by inhibiting formation of mixed bacterial biofilms ofand, thereby reducing the amount of biofilm by 52.45%, and can reduce the content of TNF-α from 131.37 pg/mL to 83.31 pg/mL and IL-8 from 147.70 pg/mL to 121.12 pg/mL in a periodontitis cell model, reduce colonization of theand thein the oral cavity by 1-2 orders of magnitude, and reduce the amount of the alveolar bone resorption from 1838.0 μm to 805.7 μm.

Strain of lactobacillus fermentum capable of preventing and/or treating periodontitis and application

The present disclosure discloses multifunctional lactobacilli capable of relieving a toxic effect of perfluorooctanoic acid (PFOA) and use thereof, and belongs to the technical field of microorganisms.CCFM1051,CCFM1052 andCCFM1053 of the present disclosure have high adsorption effect on PFOA, can significantly relieve liver oxidative stress damage and serum biochemical indicators caused by PFOA, spleen atrophy caused by PFOA exposure, imbalance of intestinal microorganisms caused by PFOA exposure and metabolic disorder of intestinal flora caused by PFOA exposure, significantly increase the content of acetic acid and propionic acid in the intestinal tract, increase the fecal water content and decrease first black stool defecation time of mice with constipation, improve proliferation and MafA gene expression of INS-1 cells under high glucose, have the potential to relieve PFOA-related diabetes, reduce occurrence of liver diseases, metabolic diseases and potential carcinogenicity, and have broad use prospects.

Multifunctionalcapable of relieving PFOA toxic effects and application thereof

Described is astrain for relieving rheumatoid arthritis and application thereof, belonging to the technical field of microorganisms. Described is astrain CCFM1078 possessing the effect of relieving rheumatoid arthritis, and shown to: promote secretion of anti-inflammatory factor IL-10 from RAW264.7 cells; reduce joint thickness, clinical score, and incidence of rats with rheumatoid arthritis; decrease levels of the pro-inflammatory cytokines TNFα and IL-1β in the serum of rats with rheumatoid arthritis; regulate the content of short-chain fatty acids in the feces of rats with rheumatoid arthritis; decrease the proportion of Th17 cells in the mesenteric lymph nodes of rats with rheumatoid arthritis; and reduce secretion of pro-inflammatory factor IL-6 from synovial cells.

Bifidobacterium breve capable of relieving rheumatoid arthritis and application thereof

The disclosure discloses a strain ofcapable of preventing and/or treatinginfection, and belongs to the technical fields of microorganisms and medicine. The disclosure provides a strain ofCCFM1118. TheCCFM1118 can inhibit, specifically embodied in that: (1) the diameter of an inhibition zone of supernatant of theCCFM1118 oncan reach 13.14 mm; and (2) theCCFM1118 can significantly reduce the adhesion ofto AGS cells. Therefore, theCCFM1118 has great application prospects in inhibiting(not for the purposes of disease diagnosis and treatment) and preparinginhibitors.

Strain ofcapable of preventing and/or treatinginfection

The disclosure discloseswith the ability to relieve atopic dermatitis and its application, and belongs to the technical fields of microorganisms and medicine. Theof the disclosure has the effects of relieving atopic dermatitis, and the effects are specifically embodied in: (1) significantly improving the degree of ear swelling in mice with atopic dermatitis; (2) significantly improving skin pathological symptoms and inflammatory cell infiltration in mice with atopic dermatitis; (3) significantly reducing the serum IgE level in mice with atopic dermatitis; (4) significantly reducing the levels of IL-4 and IL-13 in the skin tissues of mice with atopic dermatitis; and (5) significantly reducing the level of histamine in the skin tissues of mice with atopic dermatitis. Therefore, thehas great application prospects in the preparation of products for the prevention and/or treatment of atopic dermatitis.

with the ability to relieve atopic dermatitis and its application

The disclosure discloses a strain ofand application thereof in inhibiting, and belongs to the technical fields of microorganisms and medicine. The disclosure provides a strain ofCCFM1119. TheCCFM1119 can prevent and/or treatinfection, specifically embodied in that: (1) theCCFM1119 can significantly relieve the gastrointestinal symptoms of patients withinfection; (2) theCCFM1119 can significantly reduce the amount of colonization ofin patients withinfection; and (3) theCCFM1119 can significantly increase the clearance rate ofin patients withinfection. Therefore,CCFM1119 has great application prospects in the preparation of products (such as food or medicine) for preventing and/or treatinginfection.

Strain ofand application thereof in inhibiting

The present disclosure discloses a method for reducing the fructan content in food made of rice and flour using microwave heating and belongs to the technical field of food processing. Fermented products made of rice and flour are prepared using microwave heating and fructan in the products can be effectively degraded. Compared with traditional steaming, the method can remarkably reduce the fructan content in the fermented food, effectively alleviate the bowel stress sensitivity to the fermented rice and flour food by patients with irritable bowel syndrome (IBS), meet the daily dietary requirements of special crowds, has the advantages of simple process, green processing and environmental protection, and is suitable for large-scale industrial production.

Method for reducing fructan content in food made of rice and flour using microwave heating

Disclosed is linoleic acid isomerases and their application in production of conjugated linoleic acid, which belongs to the technical fields of protein engineering and microbial engineering. The linoleic acid isomerase derived fromis used to produce the conjugated linoleic acid. The recombinantcontaining the linoleic acid isomerase of the invention is added into a reaction system containing linoleic acid and react for 3 h to produce conjugated linoleic acids. The conversion rate of the conjugated linoleic acid of the invented method ranges from 12.1% to 42.1%, and the percentage of cis9, trans11-CLA in the conjugated linoleic acid can reach 84.3% to 89.1%. The invention provides a method for using microorganisms to produce conjugated linoleic acids with high safety and yield where cis9, trans11-CLA isomer is the major form in the conjugated linoleic acid products.

Linoleic acid isomerase and its application in production of conjugated linoleic acid

Disclosed is a diacylglycerol acyltransferase 1, a recombinantcontaining the diacylglycerol acyltransferase 1, and application thereof in production of triacylglycerol. The diacylglycerol acyltransferase 1 of the invention has a function of catalyzing synthesis of triacylglycerol. After the recombinantcontaining the diacylglycerol acyltransferase 1 of the invention is subjected to induction culture for 48 h, the content of total fatty acid and triacylglycerol in the recombinantcontaining the diacylglycerol acyltransferase 1 can be respectively increased by 1.94 folds and 12.09 folds as compared with those ofwithout the recombinant diacylglycerol acyltransferase 1. The instant invention provides a method for improving the ability of microorganisms to produce polyunsaturated fatty acids (PUFAs) by means of genetic engineering.

Diacylglycerol acyltransferase 1 and application thereof in production of triacylglycerol

The present invention discloses a microwave and conduction combined heating method for improving the gel strength of surimi products, belonging to the technical field of food processing. According to the present invention, surimi is first fully gelatinized by conduction heating, and then heated by microwave heating so that surimi gel can pass through a gel cracking zone quickly. This kind of microwave and conduction combined heating way can not only increase the gel strength of the surimi to achieve the desired elasticity, but also can save a lot of time and improve the production efficiency. Compared with ordinary microwave heating, the microwave and conduction combined heating method of the conduction and microwave heat preservation, i.e. holding the temperature of the surimi products for a period of time by adjusting the microwave power level at a specified temperature range, can effectively improve the gel strength of the surimi and comply with the new trend of applying microwave heating to surimi products.

Microwave and conduction combined heating method for improving gel strength of surimi products

The disclosure discloses a microwave processing equipment for continuous flow liquids, and belongs to the technical field of microwave processing. The microwave processing equipment includes a feed preheating section, a microwave heating section and a cooling section. The microwave heating section includes a microwave generation system, a waveguide system, tuners, and a microwave absorption cavity. The waveguide system includes at least two waveguides. Each waveguide is installed at the microwave feed port formed in the outer wall of the microwave absorption cavity according to a predetermined angle greater than or equal to 15&#xb0; and less than 90&#xb0;.

Microwave processing equipment for continuous flow liquids

The present disclosure discloses a microwave processing method for food made of flour and rice fermented with sourdough and belongs to the technical field of food processing. It comprises: adding a sourdough to the raw material to prepare a steamed cake batter; fermenting the batter under the dielectric constant of 2034, the loss factor of 6.39.0, the moisture content of 4555% and the water activity of 0.9200.980; and using microwave heating to obtain the microwave-steamed cake. Due to the regulating effect of the sourdough fermentation on the dielectric properties of the food material, it solves the problems of hard core, textual firmness and toughness, dryness and weak flavor caused by fast and uneven microwave heating without adding food additives; meanwhile, the sourdough fermentation process is optimized and the DY and additive amount of the sourdough are controlled to obtain the microwave-steamed cake with larger specific volume, lower hardness, more fine and uniform pores and better taste.

Microwave processing method for food made of flour and rice fermented with sourdough

The disclosure disclosesfor relieving endotoxin infection and application thereof, and belongs to the technical field of microorganisms. TheCCFM1020 of the disclosure has low immunogenicity, and can reduce the content of pro-inflammatory factors and increase the concentration of anti-inflammatory factors in the blood of hosts infected with endotoxin, up-regulate the number of Foxp3regulatory T cells and stabilize the composition of the intestinal microbiota. A pharmaceutical composition of theCCFM1020 for relieving endotoxin infection has broad application prospects.

for relieving endotoxin infection and application thereof

The present invention relates to the technical field of microbes, in particular to awhich can significantly inhibit the occurrence of colorectal cancer, and its use thereof. Thestrain CCFM164 has a deposit number CGMCC No. 14520, which has a good tolerance to gastric acid and bile salts, significantly alleviate the level of colorectal inflammation in colorectal cancer model mice, and can reduce the number of tumors in the colon and rectum of the model mice by regulating the Notch1, Notch2 signaling pathway and the expression of VEGFR2 molecule in colorectal tissue. In addition, theCCFM164 can also improve the intestinal flora population and short-chain fatty acid levels in the intestine. TheCCFM164 is used to prepare a fermented food for the inhibition of the occurrence of colorectal cancer with wild applications.

with colorectal cancer inhibition function and use thereof

Growing community of inventors

Wuxi, China

Jianxin Zhao