Labofina, S.a.

Jacques Oberto

John R Davison

Transformed yeasts comprising DNA which include at least one copy of a fragment coding for a 1,4-.beta.-N-acetylmuramidase which is expressed in the yeasts as the corresponding active protein, and a process for preparing lysozyme by growing said transformed yeasts.

Transformed yeasts for producing lysozyme, plasmids used for this

Promoters capable of ensuring expression in yeast of genes coding for heterologous polypeptides are disclosed, which comprise a DNA fragment or mutants or sub-fragments thereof, said promoter comprising a definite nucleotide sequence commencing with an EcoRI site and terminated by another restriction site. Also disclosed are vector plasmids containing the promoters, transformed yeasts comprising these plasmids, and a process for preparing polypeptides and especially a 1,4-.beta.-N-acetylmuramidase.

Growing community of inventors

Steenokkerzeel, Belgium

Jacques Oberto