University of California

San Diego State University Research Foundation

Dsm Food Specialties USA Inc.

J Bruce German

David A Mills

Carlito Bangeles Lebrilla

Daniel Garrido

Riccardo LoCascio

Daniela Barile

Luis Antonio Garay Almada

Irnayuli Rosaleida Sitepu

Kyria Boundy-Mills

Forest Rohwer

Jeremy J Barr

Oliver Fiehn

Samara Freeman

Tomas Cajka

David Sela

William Robert King

M Eric Gershwin

Milady Ninonuevo

Garlito B Lebrilla

Alvin Berger

Santiago Ruiz-Moyano

Mariana Barboza

Riccardo Locascio

David Mills

Provided are methods and yeast cultures for producing polyol lipids and polyol lipid compositions.

Methods of producing polyol lipids

Provided are compositions and methods for treating, ameliorating and preventing various infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor, where exemplary compositions are products of manufacture, a food, a drink, a nutraceutical, a dietary supplement, a formulation, a pharmaceutical or a pharmaceutical preparation comprising at least one or several of: a plurality of isolated, or substantially purified bacteriophages or prophages, or bacteriophage subunits, a milk, a milk product, milk lipid, milk fat globule (MFG) macromolecule, a milk mucin, a milk glycolipid, a milk free glycan, a milk mucin-like glycoprotein, a milk protein, a milk sugar or lactose, a milk fat or butterfat, a milk vitamin. In alternative embodiment, provided are compositions and methods for treating, preventing or ameliorating an infection, for example, an infection in the gastrointestinal tract, or bowel.

Methods for treating microbial infections using caudovirales bacteriophages

Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.

Enzymes and methods for cleaving n-glycans from glycoproteins

Provided are compositions and methods for treating, ameliorating and preventing various infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor, where exemplary compositions are products of manufacture, a food, a drink, a nutraceutical, a dietary supplement, a formulation, a pharmaceutical or a pharmaceutical preparation comprising at least one or several of a plurality of isolated, or substantially purified bacteriophages or prophages, or bacteriophage subunits, a milk, a milk product, milk lipid, milk fat globule (MFG) macromolecule, a milk mucin, a milk glycolipid, a milk free glycan, a milk mucin-like glycoprotein, a milk protein, a milk sugar or lactose, a milk fat or butterfat, a milk vitamin. In alternative embodiment, provided are compositions and methods for treating, preventing or ameliorating an infection, for example, an infection in the gastrointestinal tract, or bowel.

Products of manufacture comprising bacteriophages

Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided.

Bovine milk oligosaccharides

Enzymes and methods for cleaving N-glycans from glycoproteins

Provided are methods and yeast cultures for producing glycolipids and glycolipid compositions.

Methods of producing glycolipids

Pre-biotic compositions containing oligosaccharides and probiotic compositions useful for treatment of a subject are provided herein. Also provided are methods for administering probiotic or pre-biotic compositions.

Methods and compositions for improved digestion of milk oligosaccharides

Growing community of inventors

Davis, CA, United States of America

J Bruce German