Siemens Aktiengesellschaft

Herbert Grieb

Bernd-Markus Pfeiffer

Edmund Linzenkirchner

Karl-Heinz Kirchberg

Jun Jiang

Yue Zhuo

Frank Volkmann

Shun Jie Fan

Wolfgang Ens

Kurt Dirk Bettenhausen

Dirk Abel

Hubert Bellm

Robert Schwab

Ulrich Epple

Robert Schäfer

Michael Friedrich

Ansgar Münnemann

Philipp Orth

Gerd-Ulrich Spohr

Erich Merz

Peter Hauptmann

Michael Schüler

Thomas Müller-Heinzerling

Ingrid Maes

Lena Lohner

Hongwei Yang

Stefan Werner

Wolfgang Gutermuth

A method and device for controlling a fermenting process, wherein the method comprises collecting samples of biological cells from a fermenting tank, obtaining the state information of the current biological cells based on the collected samples, comparing the state information of the current biological cells with preset target status information to obtain the difference between the state information of the current biological cells and preset target state information, and controlling the feed rate of nutritional solution into the fermenting tank. Real time control of biological fermenting process is thus accomplished based on the state information of the biological cells during fermentation, and the consistency during fermentation is improved. Complicated mathematical modeling and man-made data analysis are not required for the method and device. Real time control of biological fermenting process is accomplished based on a feedback loop with simply calculation, and control delay is not created, and automatic control of cells statement in fermentation is achieved.

Method and device for controlling the fermentation process

A closed-loop control device for a process, in which a dead band element is connected upstream of a linear dynamic controller to reduce actuating interventions in the steady control state. If a control deviation (e) of the control loop exceeds a first threshold value (s), then the dead band element is automatically deactivated, where a control deviation (e) passed via the dead band element is uninfluenced by a set dead band in the inactive state. If the control deviation (e) then undershoots a second threshold value that is less than the first threshold value, then the dead band element is automatically re-activated. This reduces the energy consumption and wear of an actuator and improves the control behavior with regard to steady-state accuracy and the control behavior of the control loop.

Closed-loop control device

The invention relates to the online regulation of a batch process in a bioreactor. According to the invention, spectra of the actual charge in the bioreactor are recorded at successive points during the running batch process. A measuring vector is produced, for each spectrum, in the low-dimensional main constituent region by the main constituent analysis of the high-dimensional spectra. The deviation is calculated between the measuring vector and a corresponding vector of a nominal trajectory consisting of measuring vectors of a reference charge, which are determined in an earlier batch process, and at least one adjustment operation for the batch process is determined and carried out according to said deviation. The direction of the adjustment operation is maintained when the deviation determined from one point to the next decreases, and modified when the deviation determined from one point to the next remains the same or increases.

Method and arrangement for the online regulation of a batch process in a bioreactor

A method for monitoring the efficiency of a heat exchanger is provided. Heat flows from a first medium into a second medium and an actual heat flow is detected and compared with at least one reference heat flow corresponding to a respectively predetermined degree of soiling of the heat exchanger. Furthermore, a device for controlling a plant having at least one heat exchanger is described. The plant has a storage device storing at least one reference heat flow of the heat exchanger.

Monitoring of heat exchangers in process control systems

The invention relates to methods and devices for developing programs for process control systems and in particular for mathematically intensive or, as the case may be, mathematically complex programs of said kind. According to the prior art programs of said kind were written in a separate development environment and subsequently the developed algorithm was re-implemented using a programming language available for the process control system and the associated compiler. The programming and testing were consequently both time-intensive and prone to error. It is proposed to split the overall algorithm into two parts when programming programs of said kind, a) the actual control algorithm by means of which the mathematical functionality of a controller is provided, and b) the algorithm by means of which the process control system-specific functionality of the above controller is provided. The second algorithm referred to runs in the process-oriented component of the process control system and the actual control algorithm in a computer suitable for industrial application. In order to control the process the two algorithms exchange data, the decision-making authority remaining at the control system level.

Development system for process control systems as well as associated method and computer program product

A method for preventing or minimizing operational failures in a technical installation () is disclosed, in which, in accordance with influence quantities () accessible by a control system, at least one criterion () is defined so as to forecast an impending failure of one or more parts of the installation. This criterion is constantly monitored at short time intervals so as to establish a forecast of the expected failure probability. This forecast makes it possible, if necessary, to take early countermeasures () for preventing the failure of the installation or to take steps for minimizing the effects of the imminent failure.

Method for preventing or minimizing operational failures in a technical installation

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Malsch, Germany

Herbert Grieb