Pfizer Corporation

Zoetis Services LLC

Zoetis LLC

Frederick H Weber

Nigel A Evans

Robert Craig Findly

Everett Lee Rosey

Tonia Sue Agin

Rim Daoussi

An improved stabilization buffer for use in the lyophilization ofand other protozoans is disclosed. Also disclosed is an improved lyophilization method, which includes controlling ice nucleation during the freezing step.

Lyophilization methods that provide stably dehydrated protozoans for use as potent live vaccines

The present invention provides a method of inducing an immune response againstin an avian species, especially a domesticated avian species such as chicken, turkey, duck, goose and quail, by administering, in ovo, live cells of

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The invention relates to a method of vaccinating a domesticated bird against coccidiosis comprising administering in ovo an effective immnunizing dose of livesporozoites or merozoites, or a mixture thereof. In a preferred embodiment, the domesticated bird that is vaccinated is a chicken or turkey.

In ovo vaccination against coccidiosis

The invention relates to a method of vaccinating a domesticated bird against coccidiosis comprising administering in ovo an effective immunizing dose of live Eimeria sporocysts or oocysts, or a mixture thereof.

Ovo vaccination against coccidiosis

The invention relates to a method of vaccinating a domesticated bird against coccidiosis comprising administering in ovo an effective immunizing dose of live Eimeria sporozoites or merozoites, or a mixture thereof. In a preferred embodiment, the domesticated bird that is vaccinated is a chicken or turkey.

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Terre Haute, IN, United States of America

Frederick H Weber